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Promotional Offer: End of the Year 2022-image

Promotional Offer: End of the Year 2022

Buy One 4MID Kit, Get One Free ! Offer valids up to the 31st December, 2022.   Do not hesitate to beneficiate of this great offer before the end of the year 2022 ! Discover all  our 4MID kits  to assess sperm quality and male ...
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The 4MID® Kit To Optimize Semen Cryopreservation-image

The 4MID® Kit To Optimize Semen Cryopreservation

The  4MID® Kits are unique ELISA Kits commercialized by SPQI-4BioDx that allows to objectively select the best semen and therefore will improve  cryopreservation success results (by detecting poor freezers).   The  4MID® Kits  are ...
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Alt-Bio, a new partner in China-image

Alt-Bio, a new partner in China

  A new partner in China for our company !  We are glad to announce the new partnership with  AltBio   that will promote and sale all our products in China !  Do not hesitate to contact them directly at: info@altbio.com.cn Beijing ALT ...
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ProAKAP4 concentrations for bull sperm quality and fertility-image

ProAKAP4 concentrations for bull sperm quality and fertility

Thanks to our great partners from the Nantes-Atlantic College of Veterinary Medicine (France), EVOLUTION and the Autonomous University of Barcelona (Spain), we are glad to announce our new publication in Veterinary Sciences Journal !   This ...
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SHS, our new partner in Singapore-image

SHS, our new partner in Singapore

SHS , a new partner in Singapore for SPQI S.A.S ! We are glad to announce our partnership with  Scientific Hub Services  that will promote and sale all our products in Singapore Do not hesitate to contact them directly at: sales@sci-hub.com ...
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The 4MID kits available in Colombia-image

The 4MID kits available in Colombia

We have a new partner and distributor in Colombia !  You may contact them directly to buy our innovative products for sperm quality and male fertility   Tel : +57 3128922151 Tel : +57 3215538821   e-mail:  comercial@alivetsas.com ...
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New publication in Reproduction & Fertility-image

New publication in Reproduction & Fertility

A new publication with our great collaborators from the  Camel Reproduction Center  (Dubai, UAE) about the use of the Camel 4MID Kit (ref. 4VDX-19K11) in camel breeding.  Since 2017, we have been collaborating with Dr Clara MALO and Dr JA ...
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Promotional Offer - Back to School Offer-image

Promotional Offer - Back to School Offer

Back to School Promotional Offer! Do not miss our promotional offer valid up to the 31st of October, 2022 ! Buy 3 kits to assess the proAKAP4 (the 4MID kit) and get one free ! That will be 4 kits to the price of 3 ! Do not hesitate to ...
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Biolinkk, Our new partner in India-image

Biolinkk, Our new partner in India

A new partner in India for our company !   SPQI is glad to announce our new partnership with the Biolinkk company that will promote and sale all our products in India. Biolinkk Address : Third Floor,Block-B,Plot No.25 Janakpuri , New ...
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Novis Animal Solutions, our partner in USA-image

Novis Animal Solutions, our partner in USA

A great news from pet owners ! The proAKAP4 analysis is now available in USA thanks to our new partner Novis Animal Solutions ! Please do not hesitate to contact them directly as below : Novis Animal Solutions Address:  3911 Elaine ...
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XL Biotech, our new partner in Thailand-image

XL Biotech, our new partner in Thailand

XL Biotech is our great partner in Thailand that promotes and sales all our innovative products ! You may contact them directly as followed : XL Biotec Co Ltd Na Nakorn Bldg 9th Fl Na Nakorn Bldg 9th Fl 99/349 Chaengwattana ...
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AKAP4 in Koala (phascolarctos cinereus)-image

AKAP4 in Koala (phascolarctos cinereus)

A conserved role of proAKAP4 for the last 166 million years of mammalian evolution !  The proAKAP4/AKAP4 polypeptide has been recently described in spermatozoa from koala  (phascolarctos cinereus) by Skerrett-Byrne and his collaborators from ...
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Aloquence, Our new partner in Slovakia and Czech Republic-image

Aloquence, Our new partner in Slovakia and Czech Republic

All SPQI - 4BioDx products are available in Slovakia and Czech Republic thanks to our partner  Aloquence  Technologies! Please do not hesitate to contact them directly to order our products Email : info@aloquence.com Tel : +421 910 296 233 ...
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The Bull 4MID® Kit, a new tool  to assess fertility -image

The Bull 4MID® Kit, a new tool to assess fertility

Check out our last results with the  Bull 4MID® Kits to evaluate sperm quality and fertility in Holstein bulls! These results were presented in Gramado (Brazil) during the last CBRA Meeting in May 2019. In this large study, the ...
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LNCR, our new lab partner for proAKAP4 Analysis-image

LNCR, our new lab partner for proAKAP4 Analysis

We are glad to announce that the LNCR (Laboratoire National de contrôle des Reproducteurs) is now offering proAKAP4 analysis for sperm quality assessments for livestock animal and pets. You may then contact them directly at  Laboratoire ...
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Indispensable role of AKAP4 is confirmed for sperm function-image

Indispensable role of AKAP4 is confirmed for sperm function

Akap4-knockout mice line was recently generating using CRISPR-Cas9 system by Fang and collaborators.  The loss of AKAP4 led to abnormal sperm morphology, motility and infertility as previously described by Miki et al. 2008. Their studies ...
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New Partner for 4BioDx Products-image

New Partner for 4BioDx Products

We are glad to announce our partnership with  Calibre Scientific ! You may then find all our range of antibodies and ELISA kits on their website ! Calibre Scientific  represents a portfolio of niche life science companies that have an ...
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Happy New year -image

Happy New year

Happy New Year 2022 ! Bonne Année 2022 ! Feliz Ano ! To all our friends, customers, partners and distributors ! Wishing you a great, healthy and prosperous new year 2022 ! See you soon !
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Joyeux Noël! Merry Christmas!-image

Joyeux Noël! Merry Christmas!

JOYEUX NOËL! MERRY CHRISTMAS! FELIZ NAVIDAD! May Joy and Peace be with you all! Partners, customers and collaborators! And to all the members of our team : actual, past and to come :) We will stay open during all the holiday season ...
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ProAKAP4 as a marker of sperm quality in stallions-image

ProAKAP4 as a marker of sperm quality in stallions

Check out our last publication in Theriogenology from our fruitful collaborations with Linalux, Dr. ean-Philippe Lejeune and Pr Didier Serteyn and the University of Liege (Belgium). With applications of the  Horse 4MID kits , the first ...
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BREED DIAGNOSTICS, our reference lab in Australia-image

BREED DIAGNOSTICS, our reference lab in Australia

BREED DIAGNOSTICS  is our great partner in Australia to bring an innovative and functional approach in stallion semen quality assessment ! Do not hesitate to contact them directly to know more about the Horse 4MID Kit ! Tel : +61 2 4921 5637 ...
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A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory-image

A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory

Exciting results about the design of  novel chemical drugs with ß-secretase  modulatory effects that restore short-term memory and also reduce the neurofibrillary degenerating process in mouse model ! More details in a new paper from  Nicolas ...
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BIOFAR Laboratoris, our partner for the Pig 4MID Kit analyses-image

BIOFAR Laboratoris, our partner for the Pig 4MID Kit analyses

BIOFAR Laboratoris  is our great partner in Spain to bring an innovative and functional approach in boar semen quality assessment ! In Spain and Europe. Do not hesitate to contact them directly to know more about the  Pig 4MID Kit   and ...
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Chronic arsenic exposure impairs AKAP4 expression, sperm formation and fertility-image

Chronic arsenic exposure impairs AKAP4 expression, sperm formation and fertility

ProAKAP4 expression is a marker of the quality of spermatogenesis and how spermatozoa are mature and functional in ejaculates. ProAKAP4/AKAP4 are crucial for sperm flagellum formation and for sperm motility (Fang et al. 2019). Furthermore, the ...
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 Hölzel Diagnostika, our new partner-image

Hölzel Diagnostika, our new partner

Hölzel Diagnostika Handels i s our new partner in Germany, Austria and Switzerland !  We are glad of this great partnership to be at the closest to our customers in these 3 countries. Hölzel Diagnostika Handel s commercialize also all the ...
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Get a 20% off on our antibodies!-image

Get a 20% off on our antibodies!

To celebrate EUROTAU 2021and up to the 28th December 2021, we are glad to offer you a  20% discount off the list price on our antibodies  references! A great opportunity to discover our range of products in the field of neurodegenerative ...
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BIONOVUS is the Australian distributor of 4BioDx products!-image

BIONOVUS is the Australian distributor of 4BioDx products!

  BioNovus  is the main distributor of 4BioDx products in Australia! To order 4BioDx innovative products, you may then contact directly BioNovus  at  info@bionovuslifesciences.com.au . Or contact us to forward them your inquiries. ...
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A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells-image

A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells

Oxidative stress is a leading causative agent in the defective sperm function associated with male infertility. ProAKAP4 is clearly a target of oxidative stress and may be a pertinent read-out to be follow up using the 4MID approach ...
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Tsingmu Biotechnology Company, our new distributor in China-image

Tsingmu Biotechnology Company, our new distributor in China

Tsingmu Biotechnology Company  is our new distributor in China which commercialize the 4BioDx products in the area of animal reproduction! You can contact them or us directly to purchase our products! Official name: ...
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AKAP4 gene is downregulated in sterile hybrid offspring-image

AKAP4 gene is downregulated in sterile hybrid offspring

The cattleyak are the hybrid offspring between cattle and yak and combine yak hardiness with cattle productivity in Tibet and in China. Milk yield is higher in F1 hybrids than in the pure yak and often higher than in the local types of cattle. ...
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Li StarFish, distributor of 4BioDx products in Italy-image

Li StarFish, distributor of 4BioDx products in Italy

Thanks to  Li StarFish , 4BioDx products are now available in Italy. Our Italian customers can now order easily our innovative 4BioDx products via our partner and  distributor in Italy .  They may then contact directly Li StarFish at ...
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LINALUX, OUR PARTNER IN BELGIUM-image

LINALUX, OUR PARTNER IN BELGIUM

The SPQI-4BioDx team is the new partner and collaborator of  Linalux Mont-le-Soie , an European equine center located in Belgium, which has relied on  4MID® Kit  products to improve the reproductive evaluation and breeding of horses at its ...
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Cosmo Bio  USA, INC our distributor in Canada and in USA-image

Cosmo Bio USA, INC our distributor in Canada and in USA

Cosmo Bio INC is our partner since SPQI inception  and promotes all our  innovative products in North  America (USA and Canada). This Company brings Innovative biotools and services to USA and Canada. Excellent customer support enabled for SPQI ...
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AKAP4 is overexpressed in fertile water buffalo-image

AKAP4 is overexpressed in fertile water buffalo

Fu et al. 2019  have recently identified the marker AKAP4 in the spermatozoa from fertile normozoospermic buffalos, bulls or swines. They also stated that never found in the seminal fluids - Only in cells, spermatozoa. Check out their ...
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ProAKAP4: A New Parameter to Evaluate the Semen Quality-image

ProAKAP4: A New Parameter to Evaluate the Semen Quality

ProAKAP4 represents today a new molecular parameter to assess the quality of sperm.   Among biomarkers, the specificity of proAKAP4 polypeptide is to be inside the spermatozoa, more precisely in the column and ribbons of the fibrous sheath ...
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 AKAP4 and heat-induced male infertility-image

AKAP4 and heat-induced male infertility

ProAKAP4 expression is a marker of the quality of spermatogenesis and how spermatozoa are mature and functional in ejaculates. ProAKAP4/AKAP4 are crucial for sperm flagellum formation and for sperm motility (Fang et al. 2019). Furthermore, the ...
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BioNovus : The Australian distributor of 4BioDx products!-image

BioNovus : The Australian distributor of 4BioDx products!

SPQI - 4BioDx is pleased to announce that  BioNovus is now the main distributor of 4BioDx products in Australia! To order 4BioDx innovative products, you may then contact directly BioNovus  at  info@bionovuslifesciences.com.au . Or contact ...
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The 4MID®  Kit is now available for cat semen-image

The 4MID® Kit is now available for cat semen

An Innovative Test of Sperm Quality called 4MID® Kit is now available for Cat ! The  Cat 4MID® Kit  (Ref. 4VDX-19K10) is the first test that validates objectively semen quality by quantifying a protein biomarker named proAKAP4 in cat semen. ...
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Discover our Mouse / Rat 4MID® Kit

Discover our new Mouse 4MID® Kit, a complete immunoassay that allows you to quantify of the sperm protein called proAKAP4 in mouse or rat semen.   The proAKAP4 marker is a pertinent sperm parameter to be investigated in preclinical, ...
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The  4MID® kits now available in Brazil !-image

The 4MID® kits now available in Brazil !

LEAC is now the official distributor of innovative 4BioDx products in Brazil. Located in Sao Paulo,  LEAC is specialized in the sector of analytical laboratories (human and veterinary) as well as in in vitro diagnostic devices. The company ...
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AKAP4 as a marker of sperm fertility in bulls-image

AKAP4 as a marker of sperm fertility in bulls

AKAP4 transcripts were recently spotted again as the top five validated transcripts significantly increased (p < 0.05) in their level of expression in good quality bull semen compared to the poor quality bulls (classification based on their ...
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Cosmo Bio Co as a distributor of 4BioDx products in Japan-image

Cosmo Bio Co as a distributor of 4BioDx products in Japan

SPQI - 4BioDx is pleased to announce that  Cosmo Bio Co, Ltd  is now the main distributor of 4BioDx products in Japan ! Cosmo Bio Co, Ltd  is one of the biggest distributor of laboratory reagents in Japan. This well-renowed ...
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AKAP4 as an highly conserved indicator of sperm quality-image

AKAP4 as an highly conserved indicator of sperm quality

In mammals, the spermatozoa must undergo physiological changes, as named as capacitation, in the female reproductive tract prior to be able to fertilize ovocyte. A recent study from Brett Nixon and collaborators in  Mol. Cell Proteomics , ...
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The 4MID® kits are now available in Turkey !-image

The 4MID® kits are now available in Turkey !

Diagen  is now the main distributor of 4BioDx ® products in Turkey. All our innovative may be then purchased from Diagen, including the 4MID ®, the first functional test to assess sperm quality and fertility. To order 4BioDx innovative ...
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proAKAP4 in human spermatozoa-image

proAKAP4 in human spermatozoa

AKAP4 and its precursor called  pro-AKAP4  are two major proteins of the human sheath spermatozoa (Johnson et al., 1997), playing a role in sperm motility and fertility. Spermatozoa without proAKAP4/AKAP4 are abnormal, immobile and infertile ...
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GreenPure : Our Partner in South Korea-image

GreenPure : Our Partner in South Korea

Thanks to  GreenPure , all 4BioDx products are now available in Korea. Our Korean customers can now order easily our innovative 4BioDx products via our partner and distributor in South Korea.  GreenPure  is a well-renowned Korean company ...
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The 1st immunoassay to assess semen quality in pig-image

The 1st immunoassay to assess semen quality in pig

Discover our new product: The  Pig 4MID ®   kit The Pig 4MID ®  kit  (Ref. 4VDX-17K2 ) is the first test that validates objectively semen quality by quantifying a protein biomarker named pro AKAP4 in pig semen. The Pig 4MID ® kit ...
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ProAKAP4: Un Nouveau Paramètre Pour Évaluer la Qualité Du Sperme-image

ProAKAP4: Un Nouveau Paramètre Pour Évaluer la Qualité Du Sperme

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SPQI in the newspaper "La Voix du Nord" / Force Awards -image

SPQI in the newspaper "La Voix du Nord" / Force Awards

Click here   to read the article "SPQI : que les Force (Awards) soient avec la recherche académique" in the newspaper La Voix du Nord (24th of December 2016).  Follow  SPQI - 4BioDx  on  Linked In  ! All our news,  click here
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 SPQI Winner of the 2016 "Force Awards"-image

SPQI Winner of the 2016 "Force Awards"

Maryse Delehedde, President of SPQI was honored to receive two awards at the Force Awards  Ceremony held on the 24th of November 2016 at the Ankama headquarters in Roubaix. On the one hand, SPQI won the trophy in the category ...
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