Exciting results about the design of novel chemical drugs with ß-secretase modulatory effects that restore short-term memory and also reduce the neurofibrillary degenerating process in mouse model !

More details in a new paper from Nicolas Sergeant and collaborators entilted "A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory in a Mouse Model of Neurofibrillary Degeneration"
Complete paper at :
https://www.frontiersin.org/articles/10.3389/fphar.2021.679335/full

Great tools, great research!

The monoclonal pS422 antibodies (ref. 4BDX-1501) from SPQI - 4BioDx were used for both biochemical and histological analyses of Tau pathology 

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