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About us

SPQI, Products and Services

The Company SPQI (Services and Products of Quality and Innovative)  develops, produces and commercializes laboratory reagents for research (monoclonal antibodies, polyclonal antibodies, ELISA kits). Based in Lille (North of France), ...
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ProAKAP4 Concentration as A Functional Sperm Parameter

Reproductive Medecine - Male Fertility Spermatozoa without proAKAP4/AKAP4 are immotile and infertile. ProAKAP4 is required as a functional molecule for sperm motility and functionality. Spermatozoa of male mice knocked-out ...
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ProAKAP4 and male reproduction

In mammals, proAKAP4 and AKAP4 are both specifically localized to the fibrous sheath of the principal piece of the flagellum and are largely known to be  involved in the flagellum structure and sperm motility  ( Sergeant et al., 2019 ) ...
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Neurodegeneration biomarkers

Anti-Phospho Tau Antibodies as biomarkers in neurodegenerative diseases          Tau proteins are microtubule-associated proteins which  regulate polymerization and stability of microtubules  ( Weingarten et al., 1975 ). Moreover, ...
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AKAP4 is also a Cancer Testis Antigen

Cancer testis (CT) antigens are an expanding family of tumor-associated antigens that have an highly tumor restricted expression pattern and a strong immunogenicity. Among them,  AKAP-4 was initially identified as an aberrantly expressed CTA in ...
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