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About SPQI

About the Company SPQI  The Company SPQI (Services and Products of Quality and Innovative)  develops, produces and commercializes laboratory reagents for research (monoclonal antibodies, polyclonal antibodies, ELISA kits). Based in ...
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Human sperm biomarkers

Reproductive - Male Fertility  More details on the proAKAP4 protein In simple words, the proAKAP4 is the precursor of AKAP4 protein. Largely described, AKAP4 play a central role in flagellar structure, chemotaxis, capacitation and sperm ...
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Animal reproduction

In mammals, proAKAP4 and AKAP4 are both specifically localized to the fibrous sheath of the principal piece of the flagellum and are largely known to be  involved in the flagellum structure and sperm motility. In mammals, proAKAP4 is ...
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Neurodegeneration biomarkers

Anti-Phospho Tau Antibodies as biomarkers in neurodegenerative diseases Microtubule-associated Tau proteins  regulate polymerization and stability of microtubules  through their microtubule-binding domains and their level of ...
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AKAP4 is also a Cancer Testis Antigen

Cancer testis (CT) antigens are an expanding family of tumor-associated antigens that have an highly tumor restricted expression pattern and a strong immunogenicity. Among them,  AKAP-4 was initially identified as an aberrantly expressed CTA in ...
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