Reference: : 4VDX-19K11
The Camel 4MID® Kit (Ref. 4BDX-19K11) is a robust immunoassay to quantify proAKAP4 protein in camel sperm samples as a biomarker of sperm quality and male fertility.
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|Camel proAKAP4 (all breeds)|
|0 ng à 100 ng|
|fresh, chilled and frozen semen / isolated spermatozoa|
The Camel 4MID® Kit (Ref. 4VDX-19K11) contains all reagents and buffers required for the quantification of proAKAP4 protein in sperm of camelids (all breeds).
This ELISA Kit is the 1st functional test to evaluate sperm quality in camelids.
The concentration of the proAKAP4 protein is a good indicator of sperm quality and of how the spermatozoa can keep its motility high and efficient up to fecundation (Sergeant et al., 2019 ; Malo et al. 2021)
High concentrations of proAKAP4 help select semen with long lasting motility and are indicative of good spermatogenesis, giving more mature, more “normal’ spermatozoa and less tail abnormalities ratio in semen samples (Sergeant et al. 2019 ; Malo et al. 2031 ; Bastan et Askay, 2021).
Research Use Only Product (RUO) / Not for Diagnosis or Therapeutic Use.
Malo C, Carracedo S, Delehedde M, Sergeant N and Skidmore L (2021) Identification of proAKAP4 in Dromedary sperm and their correlation with monthly semen parameters. Reproduction & Fertility. Vol.2(4):268-279.
Carracedo S, Briand-Amirat L, Dordas-Perpinyà M, Ramos Escuredo Y, Delcombel R, Sergeant N and Delehedde M (2022) ProAKAP4 protein marker: towards a functional approach to male fertility. Animal Reproduction Science. Vol.247(107074):1-20. https://doi.org/10.1016/j.anireprosci.2022.107074
Riesco MF, Neila-Montero M, Palacín-Martínez C, Montes-Garrido R, Álvarez R; Boixo JC; De Paz P and Anel L and Anel-López L (2022) Establishment of innovative biomarkers to optimize cooling and cryopreservation protocols in ram sperm. Reproduction in Domestic Animals. Vol. 57(1):101.
Dordas-Perpinya M, Yanez I, Catalan J, Eddarkaoui S, Delehedde M, Sergeant N, Bruyas JF, Briand-Amirat L, and Miró J (2022) ProAKAP4 concentrations in stallion and donkey: Comparison with kinetic parameters, motility and concentration. Reproduction in Domestic Animals. Vol. 57(1):61.
Kowalczyk A, Gałeska E and Bubel A (2022) The concentration of proAKAP4 and other indicators of cryopotential of spermatozoa cryopreserved in extender with holothuroidea extract addition. Animals. Vol. 12:521.
Complete list of references on proAKAP4/AKAP4 sperm quality marker upon request at email@example.com